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SKU: 73056991995
Price: 25.08 USD
Availability: InStock
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Notably, compared with WT-resistant groups, monotherapy and combination elicited diametrically opposed trends in Mrp1 mRNA levels in KO-resistant groups across hepatic, blood, and splenic specimens: ART alone decreased hepatic and blood levels by 15.86-fold and 2.51-fold (versus 4.45-fold and 5.99-fold increases with combination), and increased splenic levels by 1.91-fold (versus a 2.56-fold decrease with combination) (Table 2 WT-R 1 versus KO-R 2 )

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Additionally, the GSH content was significantly reduced in the substantia nigra of PD patients, suggesting that GSH depletion enhances neuronal death under certain pathological conditions [6]