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Furthermore, long-term redox disturbances and interactions with endogenous antioxidant systems are often under-evaluated

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Cardiovascular disease: Patients with a history of heart disease or high blood pressure should avoid vitamin drip therapy as the high doses of certain vitamins and excess fluid may lead to cardiovascular complications

The ferroptosis inducer erastin irreversibly inhibits system xc- and synergizes with cisplatin to increase cisplatin's cytotoxicity in cancer cells