selenium supplementation glutathione peroxidase PRDX6 dictates ferroptosis sensitivity by directing cellular utilization: Molecular Cell Effects of selenium supplementation (Se)

Senescent cells normally accumulate as people age

LEF1, Lymphoid enhancer-binding factor 1

Stopping of metformin at D3 post-vaccination coincided with the known timepoint where B cells upregulate OXPHOS following ex vivo stimulation (Price et al, 2018)

When hydroxide ion donates a pair of electrons to an electrophilic atom (such as carbon here) to form a new covalent bond, it is acting as a nucleophile

To test whether the MTS pathway was supporting the TR/GR-null livers, we treated mice with single-dose challenges by inhibitors of cystine uptake (sulfasalazine, SSZ), possible cysteine uptake (2-aminobicyclo-(2,2,1)-heptane-2-carboxylic acid, BCH), conversion of methionine into cysteine by MTS (propargylglycine, PPGG, which inhibits trans -sulfuration and not the methionine cycle), or synthesis of GSH (BSO) 11