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Figure 3 T-cell activation initiates intracellular signaling cascades that ultimately result in T-cell proliferation

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Glutathione deactivates harmful substances in the body as well as aids in the uptake of amino acids

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Mechanistically, ROS generated by pyocyanin triggers the release of pro-inflammatory cytokines such as the neutrophil chemotactic factor IL-8 in a NF-B-dependent manner through the MAPK/ERK signaling (98, 99), further contributing to the pathological effects observed during P