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A trauma-related dark black spot on lip may fade in weeks, while a benign melanotic macule may remain stable for years

Increased 3-nitrotyrosine and oxidative damage in mice with a human copper/zinc superoxide dismutase mutation

HSP-mediated protection against oxidative stress and ischemic injury In addition to their structural roles, HSPs are integral components of the cardiac defense system against oxidative stress

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Some patients are efficient natural glutathione producers and see minimal benefit from oral supplements, while others have genetic predispositions to oxidative stress and respond dramatically to supplementation