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2021;35: e22830

Then, the upstream regulators, downstream effector, and crosstalk of mental ions under both physiologic and pathologic conditions will be summarized

Shklar and coworkers (173) examined the effects of methotrexate on hamster buccal pouch carcinomas generated by 9,10-dimethyl-l,2-benzanthracene and found that the methotrexate-treated group reported tumors that were larger and more anaplastic and that they progressed more quickly than the control group