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While there is no single FDA-approved schedule, most programs administer Lipo-C once or twice weekly, then adjust frequency based on laboratory trends and progress

The New York Times, Sunday, December 16, 2001, Section 14NJ page 1 of the New York edition

This change is transmitted to adjacent subunits via subunit-subunit interactions, which then cause the second subunit to switch to the R state

This process and its linkage with cytosolic GSL synthesis requires two transport steps across the chloroplast envelope, as the first reaction allowing Met to enter biosynthesis of GSLs is a deamination of Met by a cytosolic BCAT4 (Schuster et al., 2006)

10.3390/ijms24043583 71 MilanoF.MasiA.MadaghieleM.SanninoA.SalvatoreL.GalloN