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Unlike traditional hormone therapy, it does not significantly affect blood sugar or growth hormone levels, making it uniquely focused on fat metabolism

Why does one person need monthly shots for life, while another might only need a short course

Taking all this data together it seems logical or appropriate to conclude that, because IGF1-R has a different signalling pathway that can maintain lipid oxidation in the liver, FFA uptake in muscle, and activates mTORC1 could reactivate IR through tyrosine kinase activity on IRS, thus displacing serine phosphorylation, reinstituting insulin signalling