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*Correspondence: C (Linda) MC van Campen, [email protected] This article was submitted to Pharmaceutical Medicine and Outcomes Research, a section of the journal Frontiers in Pharmacology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Regulatory note: 5-Amino-1MQ is not FDA-approved for any use and has not been studied in completed human clinical trials

Because they are not easily cleared, very high intakes can build up and cause toxicity