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This element acts on the melanin and turns eumelanin into pheomelanin, which is a pigment that is commonly found in fair-skinned people

Phenocopies induced with antisense RNA identify the wingless gene

This interaction is mediated by dual binding, with FHD mainly binding to the p53 TAD and FOXO4 CR3 binding to the p53 DNA-binding domain (DBD) 38 (Figure

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