List of Abbreviations ACL anterior cruciate ligament AGE advanced glycation end product AP-1 activating protein-1 BAPN -aminopropionitrile BMP-1 bone morphogenetic protein-1 Col1a1 collagen type I alpha 1 chain Col3a1 collagen type III alpha 1 chain CRL cytokine receptor-like CSA cross-sectional area CypB cyclophilin B DOGDIC 3-deoxyglucosone-derived imidazolium ECM extracellular matrix ER endoplasmic reticulum GODIC glyoxal-derived imidazolium HH Hamburger-Hamilton HIF hypoxia inducible factor HP hydroxylysyl pyridinoline hPDL human periodontal ligament HPLC high-performance liquid chromatography Hyl hydroxylysine JNK c-Jun N-terminal kinases LH lysyl hydroxylase LOX lysyl oxidase LOXL LOX-like protein LOX-PP LOX pro-peptide LP lysyl pyridinoline LTQ lysyltyrosine quinone MAPK mitogen-activated protein kinase MCL medial collateral ligament MCP 2-mercaptopyridine-N-oxide MGO metabolite methylglyoxal MMP matrix metalloproteinase MODIC methylglyoxal-derived imidazolium P3H prolyl-3-hydroxylase P4HA prolyl 4-hydroxylase subunit alpha PCP procollagen-C-proteinase PDI protein disulfide isomerase PDL periodontal ligament PIEZO1 Piezo type mechanosensitive ion channel component 1 PLOD procollagen lysyl hydroxylase Pyr pyridinoline RT-PCR reverse transcription polymerase chain reaction SAXS small-angle X-ray scattering SDFT superficial digital flexor tendon SDS-PAGE sodium dodecyl sulfatepolyacrylamide gel electrophoresis SEM scanning electron microscopy SLRP small leucine-rich proteoglycan SNAIL snail SOX9 SRY-box transcription factor 9 TCP trans-2-phenylcylopropylamine TEM transmission electron microscopy TG transglutaminase TGF transforming growth factor beta TGFR TGF receptor Thbs1 thrombospondin-1 gene TIMP tissue inhibitor of MMP TSP-1 thrombospondin-1 References Ahmed AS, Schizas NL,J, Ahmed M, Ostenson C-G, Salo P, Hewitt C, Hart DA, Ackermann PW (2012) Type 2 diabetes impairs tendon repair after injury in a rat model
10.1158/0008-5472.CAN-19-0369 82 TewK
Pulmonary artery pressure (Ppa), tracheal pressure (Pt), and the rate of lung weight gain (LWG) were measured continuously
Importantly, both GPX4 and FSP1 highlight how two crucial regulators of ferroptosis cannot be understood solely by analysing the abundance of their mRNA
Patients with significantly impaired renal function
