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Curcumin pretreatment also preserved mitochondrial morphology and led to a reduction in intracellular ROS production

The DOCA-salt hypertensive rat model was developed as per the previous reports 6 , briefly rats were anesthetized with a mixture of ketamine (70 mg/kg body weight) and xylazine (7 mg/kg body weight) administered intraperitoneally

Together, these findings position DSIP as a multifunctional neuropeptide used in experimental models to investigate the integration of signaling pathways involved in sleep regulation, stress response, neuroprotection, and endocrine coordination

Targa Dias Anastacio, H., Matosin, N

FIGUR E | SEM micrographs and pore- si ze distributions of the Gel7.5- CZG, Gel10- C ZG, and Gel15- CZ G composite hydrogels, respec tively