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*Correspondence: Tjalf Ziemssen [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

The quality of evidence for the 28-day mortality rate was considered very low (Table 3)

Another small study found that orally administered glutathione had positive effects on people with nonalcoholic fatty liver disease following proactive lifestyle changes

For instance, a 6-week study in 66 people with type 2 diabetes found that taking 30 grams of glutamine powder daily improved multiple risk factors for heart disease and reduced both belly and body fat ( Similarly, a 2-week study using the same amount of glutamine observed decreased waist circumference, a marker for belly fat, in 39 people with overweight or obesity ( In another small study, 6 women who took glutamine supplements for 4 weeks experienced significant reductions in body weight and belly fat without making other dietary or lifestyle changes ( Yet, a study in 24 adults indicated that taking 6 grams of glutamine led to an increase in meal size, which may hinder weight loss ( Moreover, another study that examined the effects of taking a glutamine supplement in combination with exercise noted no benefits for body composition or muscle performance ( Keep in mind that all of these studies used very small sample sizes and only evaluated the short-term effects of glutamine supplements