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[91] observe that brain KBs and blood glucose are inversely correlated such that a systemic drop in blood sugar (in part due to increased uptake into the brain), is associated with increased systemic production and cerebral uptake of KBs

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GSH is highly resistant to intracellular degradation

Zn-deficient wild-type and mutant human SOD1 have been implicated in the disease familial amyotrophic lateral sclerosis (FALS), also known as Lou Gehrigs disease which affects the nerve cells in the spinal cord and the brain.29, 30 Recently, Dayal and colleagues informed that deficiency of superoxide dismutase promoted cerebral vascular hypertrophy and vascular dysfunction in hyperhomocysteinemia.31 SOD enzyme deficiency is common