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Nutrient Interactions Thiamin (vitamin B1) depletion: Very large doses of alpha-lipoic acid have caused serious toxicity in thiamin-deficient animals

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Sci Rep 7:43030 Handley RR, Reid SJ, Brauning R, Maclean P, Mears ER, Fourie I, Patassini S, Cooper GJS, Rudiger SR, McLaughlan CJ, Verma PJ, Gusella JF, MacDonald ME, Waldvogel HJ, Bawden CS, Faull RLM, Snell RG (2017) Brain urea increase is an early Huntingtons disease pathogenic event observed in a prodromal transgenic sheep model and HD cases

Be sure to inform your healthcare provider about all medications you are taking, including prescriptions, over-the-counter drugs, and herbal supplements