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10.1128/IAI.00157-18 [DOI] [PMC free article] [PubMed] [Google Scholar] 102.Romani L, Fallarino F, De Luca A, Montagnoli C, DAngelo C, Zelante T, et al

Calming visceral hypersensitivity means actively calming that pathway

In a 2023 study, Peiwen Lis team found that osimertinib prolonged QT interval, PR interval, QRS complex, and left atrial, left ventricular, and atrioventricular conduction time in isolated guinea pig hearts

We hypothesized that these agents would attenuate mucositis through anti-inflammatory and antioxidant effects associated with modulation of ferroptosis-related pathways, particularly through Nrf2-associated regulatory mechanisms