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About 10 g of dried root powder was extracted with 20 mL of acetonitrile in methanol, and the extract was centrifuged at 10,000 rpm for 15 min

Effect of folic acid supplementation on risk of new-onset diabetes in adults with hypertension in China: findings from the China Stroke Primary Prevention Trial (CSPPT)

Hum Gene Ther 14(6):545-59, 2003

Other gene mutations include those in the: HJV gene (hemojuvelin ) HAMP gene (hepcidin) TFR2 gene (transferrin receptor-2) SLC40A1 gene (ferroportin disease) FTH1 gene (mutation in the iron responsive element of H-ferritin ( FTH1 ) mRNA) Transfusional iron overload: Transfusional iron overload typically affects patients with hematologic disorders who require chronic red blood cell (RBC) transfusions, such as: Transfusion-dependent thalassemia Sickle cell disease Myelodysplastic syndrome (MDS) Ineffective erythropoiesis: Expanded erythroid marrow of patients with ineffective erythropoiesis results in erythroblast-mediated release of which inhibits the synthesis of hepcidin in the liver, resulting in increased iron absorption in the gut