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Genes 11:78

10.4049/jimmunol.1101029 185

The specific activity of the tcHGF(Xa) was ~2-fold higher than the wild-type HGF, which could be due to the different expression hosts and purification procedures

Given the lack of rare missense variants that have been annotated as likely benign or benign in ClinVar, we instead used gnomAD variants (after excluding known or suspected pathogenic variants) as a negative reference set