glutathione peroxidase amino acid sequence Frontiers The Glutathione Peroxidase Gene Family

doi: 10.1186/s13048-024-01354-y 73 YuanJLiZYuYWangXZhaoY

Tran TA, Vassileva V, Petrov P, Losanka P

Furthermore, the problems associated with vitamin C and E derivatives (e.g., limited tissue retention, targeting to the active site of oxidative stress, no targeting to specific ROS, and poor interaction with specific carriers) will largely also apply to these substances (especially because they structurally resemble vitamin C and E and share similar mechanisms of action)

For instance, mitoDFO impairs ironsulfur cluster and heme biosynthesis [147], while glycyrrhetinic acid (GA) and pyrrolo[3,2-d]pyrimidine derivatives inhibit one-carbon metabolism [148,149,150]

It simply showed the pill increased the levels of the substance in blood cells