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Two-tailed Students t-tests (for age of the study participants, age at menarche, years since menarche, and duration of menstrual bleeding), Fishers exact tests (for smoking status), and Chi square (for ethnicity, occupational status, and menstrual cycle stage) were used to compare Cases and Controls

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We noted that data were collected during different time periods (reusable, reprocessed cystoscope data were collected in 2020, and single-use, disposable cystoscope data were collected in 2021), which may introduce systematic errors in the measurement due to retrospective data collection or confounders not accounted for, such as changes in clinical practice between the 2 study years

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