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1434-C PEGINTERFERON ALFA-2b PLUS TDF TREATMENT IN ADULTS WITH HBEAG-POSITIVE CHRONIC HEPATITIS B VIRUS INFECTION: A PILOT, OPEN-LABEL, PROSPECTIVE COHORT STUDY Min Liu 1 , Lili Zuo 1 , Yuting Zhang 1 , An Xiao 1 , Yilan Wang 1 , Bing Bu 1 , Jiayi Chen 1 , Ling Zhu 1 , Wei Yue 1 , Jiawei Geng 1 and Xueshan Xia 2 , (1)The First People's Hospital of Yunnan Province, (2)Kunming University of Science and Technology Background: Expanding antiviral therapy to benefit more patients with chronic HBV infection and optimizing treatment to improve prognoses are two main objectives in current guidelines

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Front Microbiol 9:1837 Switala J, Loewen PC (2002) Diversity of properties among catalases

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Mechanistically, BCAT2 as the key enzyme mediating the metabolism of sulfur amino acid, regulated intracellular glutamate level, whose activation by ectopic expression specifically antagonize System X c inhibition and protected liver and pancreatic cancer cells from ferroptosis inducers (erastin, sorafenib, and SAS)-induced ferroptosis in vitro and in vivo (Wang K