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In addition, acylcarnitine accelerates the degradation of the PD1 protein by promoting the acetylation of the E3 ubiquitin ligase FBXO38, revealing not only the mediating role of acylcarnitine in mitochondrial communication between platelets and B cells but also its epigenetic regulatory role in regulating mitochondrial function and PD1 degradation [43]

Investigacin sobre el envejecimiento saludable: Un artculo publicado en la revista *Science* en 2023 describa los efectos sobre la esperanza de vida y la esperanza de vida saludable en modelos animales, pero las afirmaciones sobre los efectos antienvejecimiento en humanos son prematuras sin ensayos clnicos ms slidos que evalen los resultados en personas

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