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SETDB1: SET domain bifurcated 1

The cartilage loss, bony change, altered joint mechanics, and chronic inflammatory environment are not the same as a tendon strain or ligament irritation

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"BPC" stands for "Body Protection Compound." In preclinical work it is proposed to act through several overlapping pathways, including promotion of new blood-vessel growth (angiogenesis), modulation of nitric-oxide signaling, and anti-inflammatory activity, rather than through one well-defined receptor mechanism the way a conventional small-molecule drug does

Key observation: All dose groups began at 0.5mg with gradual escalation over several weeks before reaching maintenance doses