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10.4103/jcrt.JCRT_862_16 54 JiangQ.-w.KailiD.FreemanJ.LeiC.-y.GengB.-c.TanT.et al (2019)

Effective modulation of inflammation and oxidative stress for enhanced regeneration of intervertebral discs using 3D porous hybrid protein nanoscaffold

Most anti-PD-L1/PD-1 monoclonal antibodies sensitize RT only to a certain extent, due to the fact that intracellularly localized PD-L1 proteins are unaffected by these antibodies, and thus cytoplasmic PD-L1 proteins accelerate DNA damage repair (DDR), thereby inducing radiation therapy resistance [251]