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The copper ion present in AHK-Cu may have a role in the enzyme activity that may promote the creation of collagen and elastin

Pharmacol Therap 229:107929

The 2 individual patient-reported components (stool frequency and rectal bleeding) are part of the Mayo score and were not powered for statistical significance Correlation of depicted PROs to Week 6 and Week 52 primary end points was not evaluated in the analysis GEMINI I TRIAL EXPLORATORY END POINTS: PATIENT-REPORTED OUTCOMES Overall population compared with placebo Not powered for statistical significance

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Hair tests dont show recent impairment, but they do reflect long-term drinking patterns