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Behavioral therapy also fails to address the biological cause: a child cannot train out sensory overload or emotional volatility when their antioxidant systems are depleted

Relative lipid ROS levels in ALDH18A1 -KO or YG1702(10 ug/ml)-treated PDLCs and SNU449 cells cultured in dFBS medium pre-treated with MJP plus vehicle or spermine (10 uM) for 24 h, followed by RSL3(1 M) and erastin (5 M) treatment for 10 h

2 ITS mechanism in mesenchymal stem cell maintenance

In OA studies, direct intra-articular injection of Fer-1 into mouse or rat models significantly reduced the accumulation of lipid peroxidation end-products like MDA and 4-HNE in cartilage tissue, alleviated the degree of ECM degradation, and improved overall joint pathology scores

Metabolomic data generated or analyzed during this study are included in this article and its supplementary tables and are available from the corresponding author on request