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Through the diet, carotenoids also enter the human body, where they can take on a similar role particularly in the eyes

On the contrary, superparamagnetic iron oxide nanoparticles (SPIONs) are used in MRI as transverse relaxation time (T 2 ) contrast agents since, in addition to their low toxicity and citocompatibility, they show excellent magnetic properties [24,25,26,27]

Such differences in alkaloid profile could have implications for biological activity, a possibility that we explore in the next sections

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Still, these side effects can be mitigated by introducing the compound slowly, applying it every other day, or using a lower concentration of the active ingredient