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Neurotoxicology 46 , 1924 (2015)

The pharmacological chaperone isofagomine increases the activity of the Gaucher disease L444P mutant form of beta-glucosidase

Data availability statement The original contributions presented in the study are included in the article/Supplementary material, further inquiries can be directed to the corresponding author

Its unique phytochemical composition contains a distinct and complex mixture of cannabinoids, terpenes and other bioactive compounds, such as Cannabigerol, -caryophyllene and -bisabolol, that act synergistically and contribute to its overall pharmacological effects ("entourage effect")

3.2.2 Tissue barrier integrity loss Over the 12-day experimental period, Crystalline silica, Amiodarone, and the reference materials LPS and Sulforaphane showed no effects on barrier integrity in either laboratory