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Modulating NF-B can therefore resensitise tumour cells to therapeutic agents and improve treatment outcomes [38, 186, 236]

Sorafenib upregulated sodium/glucose cotransporter 2 (SGLT2) in cardiomyocytes, promoting glucose and sodium influx, calcium overload, and ultimately cell ferroptosis

Chen X, Wang L, Denning KL, Mazur A, Xu Y, Wang K, Lawrence LM, Wang X, Lu Y (2024) Hepatocyte-specific PEX16 abrogation in mice leads to hepatocyte proliferation, alteration of hepatic lipid metabolism, and resistance to high-fat diet (HFD)-induced hepatic steatosis and obesity