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This overlap suggests that FOXO4s activation by oxidative stress and inflammation might follow similar mechanisms, pointing to a broader role of FOXO4 in stress and immune response contexts

47:268279 Wakabayashi K, Tanji K, Odagiri S, Miki Y, Mori F, Takahashi H (2013) The Lewy body in Parkinsons disease and related neurodegenerative disorders

joint involvement with pain/swelling/erythema), in the context of the patients history, with supporting evidence of elevated serum urate levels at a time other than during an acute attack Elevated serum urate levels alone are not diagnostic of gout, but may inform lifestyle changes (if relevant) and subsequent follow-up testing Treat gout flares with a NSAID, prednisone or low-dose colchicine

doi:10.1038/s41422-019-0153-8 Hur EM, Lee BD

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