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Farnesoid X receptor activation by the novel agonist TC-100 (3, 7, 11-Trihydroxy-6-ethyl-5-cholan-24-oic Acid) preserves the intestinal barrier integrity and promotes intestinal microbial reshaping in a mouse model of obstructed bile acid flow

The main mechanism for premature senescence is signaling from Treg cells to other T cells (effector, CD4, and CD8) 98

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