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Endothelial dysfunction and aging Aging may alter the structure and function of vascular components, such as the endothelium, intimas and smooth muscle cells, resulting in an increase in the risk of development of cardiovascular and cerebrovascular diseases, which are related to hypertension

59 HSC aging can be induced by various mechanisms

[DOI] [PubMed] [Google Scholar] Iwase S., Kawaguchi T., Yotsumoto D., Doi T., Miyara K., Odagiri H., Kitamura K., Ariyoshi K., Miyaji T., Ishiki H., Inoue K., Tsutsumi C., Sagara Y., Yamaguchi T

They inflict pain, lead to functional impairment and disability, and generate a massive financial burden for families and society ( Ferroptosis was proposed as a novel form of cell death in 2012

Severe edema of the lamina propria and continuous diffuse edema of the submucosa was also evident (Figure 23A)