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F., Pinna, F., Meloni, F., Ladu, S., Pellegrino, R., Sini, M., et al

By inducing mild oxidative stress, they can activate endogenous defense systems, particularly the Nrf2 pathway, which plays a central role in regulating antioxidant responses

SM, Skeletal Muscles

In another aspect of this embodiment, the compound has the structure of formula (III): wherein the C 2-4 alkyl is selected from the group consisting of ethyl, isopropyl, n-propyl, butyl, and t-butyl, or an N-oxide, crystalline form, hydrate, or pharmaceutically acceptable salt thereof

Modulation of hydrogen peroxide-induced oxidative stress in human neuronal cells by thymoquinone-rich fraction and thymoquinone via transcriptomic regulation of antioxidant and apoptotic signaling genes