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DOR was most commonly prescribed as part of complex ART regimens including several anchor agents (i.e., INSTI, protease inhibitor [PI], NNRTI, entry inhibitor): 47% were prescribed DOR plus 2 anchor agents and 23% were prescribed DOR plus one anchor agent (Table 2)

The specific combination of phytochemicals encapsulated within NPs, along with their size and shape characteristics, determines their overall impact on different regulatory pathways involved in diabetes management ( Figure 3 )