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Similarly, lead treatment also significantly inhibited the activities of SOD, GPX, and CAT and increased the accumulation of nitric oxide (NO) and MDA to induce oxidative stress and activate MAPK/NF-B signal pathway to cause splenic necrosis [102]

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In addition, DPF2 (a subunit of cBAF) in SMARCB1-rescued cells (+ SMARCB1) localized to regions proximal and distal from the TSS of the SLC7A11 locus (Fig