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Highly active areas, such as the brain, may rapidly deplete stores

De la Pena JA, Rubio OV, Cano JP et al

In one double-blinded controlled study of ALA therapy for BMS, there was a significant improvement in pain, compared with placebo, with the majority of test subjects showing some improvement after 2 months, and more than 70% of the subjects maintained this improvement at 1 year

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In experimental models it is used to explore mechanisms of tissue regeneration, angiogenesis, inflammatory modulation and maintenance of gastrointestinal barrier integrity