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Masaldan S, Clatworthy SAS, Gamell C et al (2018) Iron accumulation in senescent cells is coupled with impaired ferritinophagy and inhibition of ferroptosis

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The modulation of these histone marks by IF-induced autophagy represents a key mechanism by which fasting influences the epigenome, potentially contributing to its beneficial effects on health span and longevity across generations [89, 91]

This seven-amino-acid synthetic peptide was derived from spadin, itself a fragment of the sortilin protein