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[10,11] The demonstration of some ARVs with the different mechanisms of action, such as zidovudine (AZT) and indinavir in animal models, were reported to induce PH through endothelin-1 production, endothelial mitochondrial dysfunction, and excessive ROS generation

170 , 178 In those individuals with GS deficiency and oxoprolinemia, administration of oral sodium bicarbonate or citrate is necessary to control acidosis

Thus, our study demonstrates the GPx1-centered signaling module determining cell fate in cancer cells

Cytosolic NAD + is synthesized by NMNAT2 localized in the cytoplasm and Golgi, where it is essential for glycolysis 82

Bhattacharya, S