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1,2 Serum vitamin B 12 levels may be artificially elevated in patients with alcoholism, liver disease, or cancer because of decreased hepatic clearance of transport proteins and resultant higher circulating levels of vitamin B 12

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According to the authors, this is "consistent with ALCAR's potential efficacy for depressive symptoms." In another study, ALCAR was found to improve the clinical condition of patients with degenerative cerebellar ataxia, a condition resulting in the loss of control of bodily movements

References Abhinandan K, Skori L, Stanic M, Hickerson NM, Jamshed M, Samuel MA (2018) Abiotic stress signaling in wheatan inclusive overview of hormonal interactions during abiotic stress responses in wheat