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26042617, May 2015, doi: 10.1111/bph.13083

Repetitive closed-head impact model of engineered rotational acceleration (CHIMERA) injury in rats increases impulsivity, decreases dopaminergic innervation in the olfactory tubercle and generates white matter inflammation, tau phosphorylation and degeneration

Additionally, 69% of participants achieved at least 10% weight loss, a threshold associated with clinically meaningful health improvements

Evening administration is therefore best described as a research convention the natural thing to try when investigating a compound named for sleep rather than an optimized or validated schedule

Their recently discovered enrichment in two additional layers within focal adhesions and their role in regulating myosin IB and IC affinity to actin suggest they modulate the precise dynamics of adhesion formation and turnover that is needed for persistent migration