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The procedural difference matters more than most assume

Cationic liposomes can interact with the anionic eye surface, prolonging the eye retention time and enhancing tacrolimus in the cornea.FK506 liposomes have also been shown to reduce ROS and DED-related inflammatory factors, which have excellent potential for treating ocular diseases [218]

The oxidation states of the low-potential clusters are the oxidized [2Fe 3+ , 2Fe 2+ ] and the reduced [Fe 3+ , 3Fe 2+ ] forms, while the oxidation states for the high potential clusters switch between the reduced [2Fe 3+ , 2Fe 2+ ] and the oxidized [3Fe 3+ , Fe 2+ ] forms

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USA 106 , 1894818953 (2009)