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The NAD+ connection NAD+, nicotinamide adenine dinucleotide, is one of the most important molecules in your cells

The heartburn comes from acid reaching the esophagus through a mechanical process (delayed emptying plus increased pressure), not from any toxic or erosive effect on stomach tissue

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The reason is practical: it binds well to transport proteins in the blood and is retained longer than some other forms, so injections can be spaced months apart rather than given frequently

doi: 10.1038/sj.ijo.802202