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In this work, the genetic heterogeneity of myeloma cells is reflected in the bortezomib sensitivity, both in patients and in myeloma cell lines

Certain people should have extra screening, tighter monitoring, or alternative strategies: pregnancy or trying to conceive active cancer or recently treated cancer without oncology clearance uncontrolled autoimmune disease with high inflammatory burden severe allergic history or unpredictable reactions to injectables complex medication regimens that increase interaction concerns advanced liver or kidney disease that alters clearance and risk Cautious does not automatically mean no. It means individualized planning

Netrin-1 upregulates GPX4 and prevents ferroptosis after traumatic brain injury via the UNC5B/Nrf2 signaling pathway

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Both have their place, and they are not mutually exclusive