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MS/MS spectra were collected for LGSH using parallel reaction monitoring mode (PRM) in positive mode with a precursor ion of 320.1122 m/z, an MS/MS resolution of 17,500 and AGC target of 1 10 5 , a maximum IT of 100 ms, and stepped-wise collision energies of 10, 25 and 35

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the clinical relevance of this finding in humans is unknown, and in UK and EU prescribing information this is noted as a precaution rather than a formal contraindication but individuals with a personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia type 2 (MEN2) should discuss this with their doctor

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Ariyasu, S., Hayashi, H., Xing, B