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This is clinically relevant because obesity itself is associated with numerous health conditions that might influence treatment tolerance, including metabolic syndrome, cardiovascular disease, sleep apnea, and hepatic steatosis

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With the use of oral supplements, and when vitamin B12 intake has been low or inconsistent for some time, an ample dosage of 500 g is advised for several months before it is lowered

Dosage and frequency are tailored to your metabolism, activity level, and health goals

The ideal therapeutic goal is to restore the balance between fission and fusion