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Moreover, recent experimental results show that two more histidine residues located in the C terminal region of PrP provide protection against neurotoxicity, when this is exerted from the N terminal region (Schilling et al., 2020)

To view a copy of this license, visit About this article Cite this article Tabassum, S., Ahmad, S., Madiha, S

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As the deficiency progresses, more specific neurological signs and symptoms may develop, such as numbness or tingling in the hands and feet, difficulty walking, memory issues, or mood changes, such as irritability or depression