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This protective effect may be mediated by its active ingredients that can cross the blood-brain barrier and enter the brain tissue, but the blood brain permeability has not been examined

Low levels are common in people with chronic inflammation and allergic symptoms

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Hypoploid cell assessment was measured on ethanol-permeabilised U937 cells exposed or not to 10 ng ml 1 of TNF- cultured overnight with or without 400 ng ml 1 of cycloheximide (CHX), by staining with PI, as previously described (Mollereau et al, 1996)

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