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Description

Braun, E

2.1.2 Adenosine axis of metabolism-related receptors (CD39/CD73) The unique expression pattern of metabolism-related receptors on the surface of exhausted T cells reveals the profound impact of metabolic regulation in the TME on T-cell fate

The rate limiting amino acid is cysteine, and this is why the supplement N-Acetyl Cysteine (NAC) helps boost glutathione levels (9)

OCR and ECAR readings were determined for three cycles (2-min mixing and 5-min measuring), and the baseline measurements were the average of the last three readings before oligomycin addition (1 M final concentration)