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Several studies suggest that SSRIs such as sertraline can cause sexual dysfunction in the areas of low libido and erectile dysfunction, which may be due to changes in serotonin, which causes changes in neurotransmission in the penis ( Another report showed that curcumin may reduce the testicular toxicity induced by sertraline in rats by inhibiting oxidative stress

The regulation of GSH synthesis is determined by the availability of its constituent amino acids, especially cysteine and glutamate, and the enzymatic activity of GCL