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Once into the brain, Vit B12 interacts with genes (LRRK2), proteins (synuclein and Lewy bodies), neurotransmitters (dopamine, Acetylcholine (Ach)) and metabolites that do impact on CNS hemostasis

Daratumumab monotherapy for patients with intermediate or high-risk Smoldering Multiple Myeloma (SMM): centaurus, a randomized, open-label, multicenter phase 2 study

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By using the Electron Paramagnetic Resonance (EPR) spin trapping technique, the transitory formation of hydroxyl radical, which has a half life of 1 10 -9 sec at 37C, has been demonstrated [130]

2 Shanghai Institute for Biomedical and Pharmaceutical Technologies, National Health Commission Key Laboratory of Reproduction Regulation, Shanghai, China